The biological pathways of Alzheimer disease: a review
نویسندگان
چکیده
Alzheimer disease is a progressive neurodegenerative disorder, mainly affecting older people, which severely impairs patients' quality of life. In the recent years, number affected individuals has seen rapid increase. It estimated that up to 107 million subjects will be by 2050 worldwide. Research in this area revealed lot about biological and environmental underpinnings Alzheimer, especially its correlation with ?-Amyloid Tau related mechanics; however, precise molecular events pathways behind are yet discovered. review, we focus our attention on mechanics may lie development. particular, briefly describe genetic elements discuss specific processes potentially associated disease.
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ژورنال
عنوان ژورنال: AIMS neuroscience
سال: 2021
ISSN: ['2373-7972', '2373-8006']
DOI: https://doi.org/10.3934/neuroscience.2021005